Table 1.

NGF-sensitive late-response gene products, transcriptionally regulated in PC12 cells via AP-1- or CREB-binding sites

(1) Latexin1-a
(2) IL-1α1-b
(3) Choline acetyltransferase1-c
(4) Neurofilament, light (NF-L)1-d
(5) Neuropeptide Y (NP-Y)1-e
(6) VGF1-f
(7) Dopamine β-hydroxylase1-g
(8) Tyrosine hydroxylase1-h

  • Shown are proteins for which expression levels or mRNA levels are upregulated by NGF in PC12 cells and for which AP-1 proteins and/or AP-1- or CREB-binding elements in respective gene promoter regions are implicated in controlling transcription. All of the proteins listed are products of late-response genes PC12 cells.

  • ↵F1-a Miyasaka et al., 1999;

  • ↵F1-b Alheim et al., 1996;

  • ↵F1-c Bejanin et al., 1992; Pongrac and Rylett, 1998;

  • ↵F1-d Reeben et al., 1995;

  • ↵F1-e Holliday et al., 1995;

  • ↵F1-f D'Arcangelo et al., 1996; Di Rocco et al., 1997; Luc and Wagner, 1997;

  • ↵F1-g Huang and Kao, 1996; Swanson et al., 1998;

  • ↵F1-h Gizang-Ginsberg and Ziff, 1990;Nagamoto-Combs et al., 1997.