Relative potencies of opioid agonists in inhibiting forskolin stimulated intracellular cAMP production for the cloned μ-opioid receptor
| Ligand | EC50(nm) | Maximum inhibition (%) |
|---|---|---|
| Endomorphin-1 | 6.3 ± 2.0 | 51.0 ± 4.7 |
| Met-enkephalin | 1.7 ± 0.4 | 63.0 ± 4.6 |
| Morphine | 7.1 ± 1.6 | 73.0 ± 2.1 |
| DAMGO | 2.1 ± 0.6 | 78.3 ± 2.9 |