Physiologic values for experiment 10 (rat forebrain ischemia–intravenous MnTE-2-PyP5+ after treatment)
| Vehicle (n = 23) | MnTE-2-PyP5+ 150 ng (n = 20) | MnTE-2-PyP5+ 300 ng (n = 20) | |
|---|---|---|---|
| Preischemia body weight (gm) | 288 ± 13 | 288 ± 12 | 297 ± 16 |
| Day 5 body weight (gm) | 304 ± 20 | 306 ± 19 | 308 ± 24 |
| 10 min before ischemia | |||
| MAP (mmHg) | 85 ± 19 | 86 ± 20 | 92 ± 18 |
| Arterial pH | 7.41 ± 0.04 | 7.39 ± 0.05 | 7.40 ± 0.03 |
| PaCO2 (mmHg) | 37 ± 2 | 38 ± 4 | 37 ± 2 |
| PaO2 (mmHg) | 162 ± 25 | 174 ± 35 | 173 ± 31 |
| Glucose (mg/dl) | 111 ± 8 | 105 ± 12 | 114 ± 17 |
| Hematocrit (%) | 42 ± 2 | 42 ± 2 | 42 ± 2 |
| Pericranial temperature (°C) | 37.4 ± 0.3 | 37.5 ± 0.2 | 37.4 ± 0.3 |
| 10 min after termination of ischemia | |||
| MAP (mmHg) | 109 ± 11 | 112 ± 14 | 111 ± 8 |
| Arterial pH | 7.31 ± 0.09 | 7.31 ± 0.07 | 7.28 ± 0.08 |
| PaCO2 (mmHg) | 41 ± 4 | 40 ± 3 | 42 ± 4 |
| PaO2(mmHg) | 187 ± 26 | 197 ± 33 | 198 ± 33 |
| Pericranial temperature (°C) | 37.5 ± 0.1 | 37.4 ± 0.3 | 37.4 ± 0.2 |
All values are mean ± SD. MAP, Mean arterial pressure; PaCO2, arterial carbon dioxide partial pressure; PaO2, arterial oxygen partial pressure. There were no differences among groups.