Table 1.

Adenylyl cyclase activity in mice carrying the Gnas (−/+) mutation in the C57BL/6J background

Brain regionC57BL/6J (+/+)C57BL/6J (−/+)
Hypothalamus2268  ± 1421748  ± 107*
Cerebellum2182  ± 1951682  ± 97*
Hippocampus673  ± 50520  ± 25*
Frontal cortex1566  ± 1181230  ± 173*
Brainstem1179  ± 61942  ± 77*

  • (+/+), Wild type; (−/+), Gnas.

  • ↵* p < 0.05; n = 5–7 per group. Units, picomoles per milligram protein per 20 min.