Inhibitor | Caspase | Sham | Inhibitor alone | 1 hr MCAO | Inhibitor + 1 hr MCAO |
---|---|---|---|---|---|
YVAD-CMK | Caspase-1 | 210 ± 9.5 | 236 ± 21.9 | 326 ± 9.54-150 | 207 ± 21.84-151 |
Caspase-3 | 52.2 ± 2.5 | 36.5 ± 14.2 | 209.5 ± 2.54-150 | 59.7 ± 204-151 | |
Caspase-8 | 221 ± 12.71 | 237.61 ± 15.25 | 818.36 ± 14-160 | 178.92 ± 10.94-151 | |
IETD-FMK | Caspase-8 | 219.7 ± 12 | 149.6 ± 19.3 | 816.13 ± 14-150 | 131.2 ± 9.64-151 |
Caspase-3 | 124.8 ± 18 | 70.7 ± 13.3 | 389 ± 834-150 | 84 ± 17.84-151 | |
Caspase-1 | 46.75 ± 0.45 | 52.65 ± 2.5 | 163.85 ± 18.614-150 | 54.64 ± 5.64-151 |