Comparison of mIPSC properties recorded in juvenile hypoglossal motoneurons
| Types of mIPSCs | Events recorded in the absence of pentobarbital | Events recorded in the presence of pentobarbital | ||||||
|---|---|---|---|---|---|---|---|---|
| Decay (msec) | Amplitude (pA) | Rise time (msec) | n | Decay (msec) | Amplitude (pA) | Rise time (msec) | n | |
| Control | 13.0 ± 4.3 | 51.1 ± 25.0 | 1.5 ± 0.1 | 13 | 33.2 ± 14.4 | 51.5 ± 12.2 | 1.8 ± 0.3 | 16 |
| GABA | 19.5 ± 7.3* | 41.3 ± 12.7 | 1.8 ± 0.4 | 13 | 66.3 ± 21.2* | 38.8 ± 20.4 | 3.0 ± 0.6 | 9 |
| Glycine | 6.9 ± 3.3 | 52.9 ± 19.9 | 1.3 ± 0.4 | 13 | 9.3 ± 2.4 | 55.2 ± 20.9 | 1.5 ± 0.2 | 6 |
Values are means ± SD. Decay kinetics were measured as the time for mIPSC to decay to 37% of its peak amplitude.
↵* GABAergic mIPSC decay times were significantly prolonged by pentobarbital (p ≤ 0.05; t test).n indicates the number of cells studied.