SD duration (hr) | Sleep latency (min) | |||
---|---|---|---|---|
AK | D2 | AK | D2 | |
35 min (day 9) | 0.96 (0.04) | 0.98 (0.08) | 12.2 (2.8) | 9.6 (3.5) |
35 min (day 4) | 1.16 (0.04) | 1.20 (0.11) | 19.7 (2.4) | 16.1 (4.4) |
70 min | 1.66 (0.06) | 1.61 (0.06) | 15.6 (4.2) | 7.2 (2.9) |
140 min | 2.74 (0.04) | 2.64 (0.06) | 8.5 (3.2) | 3.5 (1.6) |
6 hr | 6.27 (0.06) | 6.48 (0.22) | 2.1 (1.1) | 0.6 (0.5) |
9 hr | 9.32 (0.07) | 9.61 (0.16) | 0.3 (0.8) | −0.3 (0.1) |
p | <0.0001 | <0.0001 | <0.0001 | 0.0008 |
The durations of the SDs in the dose–response study did not differ between strains [mean (SEM); two-way ANOVA factor strain: p = 0.3, factor dose: p < 0.0001, interaction: p = 0.4; Tukey's range test: 9 hr > 6 hr > 140 min > 70 min > 35 min (day 4) = 35 min (day 9); p < 0.05; n = 12 per dose except 6 hr SD; n = 14; data from both strains pooled for the Tukey test]. Sleep latency varied with SD dose and genotype [two-way ANOVA factor strain: p = 0.02; factor dose: p < 0.0001; interaction: p = 0.7; Tukey's range test: 9 hr = 6 hr = 140 min < 140 min = 35 min (day 9) = 70 min < 35 min (day 9) = 70 min = 35 min (day 4); p < 0.05; data from both strains pooled]; however, for none of the SDs did the two strains differ significantly (t tests; p > 0.1). Probability (p) values indicated in this table were obtained from the one-way ANOVA with factor SD dose.