Table 2.

Duration of the sleep deprivation and of recovery sleep latency

SD duration (hr)Sleep latency (min)
AKD2AKD2
35 min (day 9)0.96 (0.04)0.98 (0.08)12.2 (2.8)9.6 (3.5)
35 min (day 4)1.16 (0.04)1.20 (0.11)19.7 (2.4)16.1 (4.4)
70 min1.66 (0.06)1.61 (0.06)15.6 (4.2)7.2 (2.9)
140 min2.74 (0.04)2.64 (0.06)8.5 (3.2)3.5 (1.6)
6 hr6.27 (0.06)6.48 (0.22)2.1 (1.1)0.6 (0.5)
9 hr9.32 (0.07)9.61 (0.16)0.3 (0.8)−0.3 (0.1)
p<0.0001<0.0001<0.00010.0008
  • The durations of the SDs in the dose–response study did not differ between strains [mean (SEM); two-way ANOVA factor strain: p = 0.3, factor dose: p < 0.0001, interaction: p = 0.4; Tukey's range test: 9 hr > 6 hr > 140 min > 70 min > 35 min (day 4) = 35 min (day 9); p < 0.05; n = 12 per dose except 6 hr SD; n = 14; data from both strains pooled for the Tukey test]. Sleep latency varied with SD dose and genotype [two-way ANOVA factor strain: p = 0.02; factor dose: p < 0.0001; interaction: p = 0.7; Tukey's range test: 9 hr = 6 hr = 140 min < 140 min = 35 min (day 9) = 70 min < 35 min (day 9) = 70 min = 35 min (day 4); p < 0.05; data from both strains pooled]; however, for none of the SDs did the two strains differ significantly (t tests; p > 0.1). Probability (p) values indicated in this table were obtained from the one-way ANOVA with factor SD dose.