Intrinsic and synaptic properties of discharging and nondischarging inhibitory and excitatory neurons
| Vm (mV) | Threshold-Vm(mV) | Rm (MΩ) | Isynaptic (pA) | |
|---|---|---|---|---|
| Discharging interneurons | −67 ± 1.0 (39) | 27.0 ± 1.1 (39) | 243 ± 24 (26) | 359 ± 43 (33) |
| Nondischarging interneurons | −69.3 ± 1.3 (18) | 23.1 ± 1.8 (18) | 414 ± 64 (14)* | 72 ± 17 (15)1-160 |
| Excitatory neurons | −66 ± 2.0 (19) | 22.0 ± 2.4 (17)* | 553 ± 56 (19)1-160 | 70 ± 13 (15)1-160 |
All the excitatory neurons included in this analysis did not discharge.Vm, Resting membrane potential; Rm, input resistance. Isynaptic was the peak monosynaptic current elicited by thalamocortical stimulation at a holding potential of −71 mV; stimulus levels were ≤100 μA for the discharging interneurons, and ≥100 μA for the nondischarging cells (inhibitory or excitatory). Values are mean ± SEM; the number of cells examined is indicated in parentheses. Asterisks indicate two-tailed p values for differences in mean compared with discharging inhibitory interneurons.
↵* p < 0.05;
↵F1-160 p < 0.0001.