Table 1.

Number of motoneurons in agrin null mutant mice (agrin−/−) and their wild-type and heterozygous (control) littermates

ControlAgrin−/−% increase
Trochlear215  ± 12 (11)271  ± 13 (7)1-16026
Trigeminal motor1073  ± 37 (9)1339  ± 58 (6)1-16025
Facial4490  ± 200 (5)4734  ± 89 (5)5
Hypoglossal2024  ± 79 (2)2412  ± 98 (3)19
  • Control and agrin−/− values are the average ± SEM. The values in parentheses indicate the number of animals examined (

  • F1-160 p < 0.01). Percentages (%) refer to the increase in the number of motoneurons with respect to the controls.