Quantification of ultrastructural variables in mossy fiber terminals from wild-type and synapsin III knock-out mice
| Morphological variables | Wild type | Knock-out |
|---|---|---|
| Vesicle density, number/μm3 | 5608 ± 137 | 5878 ± 106 |
| MFT profile area, μm2 | 3.89 ± 0.14 | 4.03 ± 0.17 |
| Mitochondrial profile area, μm2 | 0.24 ± 0.02 | 0.26 ± 0.03 |
| Spine profile area, μm2 | 0.82 ± 0.05 | 0.92 ± 0.05 |
| Net MFT area, μm2 | 2.85 ± 0.11 | 2.86 ± 0.12 |
| Number of mitochondria profiles/MFT profile | 4.18 ± 0.45 | 4.30 ± 0.44 |
| Number of spines/MFT profile | 3.36 ± 0.11 | 4.13 ± 0.27* |
Data are expressed as mean ± SEM.
↵* p < 0.05, compared with wild type by two-tailed unpaired Student's t test.