Table 3.

Excitability and responsiveness to passive movement of the arm area of MI in the normal and MPTP states

Monkey SMonkey Z
NormalMPTP3-aNormalMPTP3-a
A. Intracortical microstimulation
n (stimulation sites)71557461
 % (n) eliciting movement of the contralateral arm3-b94% (67)100% (55)74% (55)59% (36)
 Threshold (μA)3-c (mean ± SEM)19.5  ± 1.218.4  ± 0.723  ± 231  ± 23-160
B. Somatosensory examination: responsiveness
n (pooled responses to three arm joints)180147200174
 % (n) positive responses3-b69% (124)82% (121)3-16056% (112)70% (122)3-160
C. Somatosensory examination: specificity
n (recording sites)72568064
 Median number of contralateral arm joints eliciting multiunit responses3-d233-150123-150
 Median number of contralateral arm and leg joints eliciting multiunit responses3-d233-1501.53.53-165
  • F3-a All tests compare between the normal and the MPTP states. p values:

  • F3-150 <0.05;

  • F3-160 <0.01;

  • F3-165 <0.001.

  • F3-b Two-sided χ2 test. “Questionable” responses removed.

  • F3-c Two-sided two-sample ttest.

  • F3-d Two-sided Wilcoxon rank-sum test.