Table 1.

Synoptic view of the antibodies used in the present study

AntigenAntiserumLocalizationrd Anomalies
PKCαMouse anti-PKCαRod bipolar cellsAbsence of dendritic arborization
Rabbit anti-PKCα
L7Mouse anti-L7Rod bipolar cellsAbsence of dendritic arborization
GOαMouse anti-GOαRod bipolar cellsAbsence of dendrites
On-cone bipolar cellsLate loss of dendritic arborizations
CaldendrinRabbit anti-caldendrinCone bipolar cellsLate loss of dendritic arborizations
Neurokinin 3 receptor (NK3)Rabbit anti-NK3Cone bipolar cellsLate loss of dendritic arborizations
CalbindinMouse anti-calbindin DHorizontal cellsLoss of organization, hypertrophy of
Rabbit anti-calbindin D cell bodies
Neurofilament 200 kDaMouse anti-neurofilament 200 kDaHorizontal cells axonal arborizationsAnomalous development, loss of thin fibers, widening of the arbors
Rabbit anti-neurofilament 200 kDa
mGluR6Rabbit anti-mGluR6On-bipolar cells dendritic tipsAltered localization, decreased staining
Glutamine synthetase (GS)Mouse anti-GSMüller cells
Glial fibrillary acidic protein (GFAP)Rabbit anti-GFAPMüller cellsIncreased reactivity
Disabled 1Rabbit anti-disabled 3All amacrine cells
Choline acetyl transferase (CHaT)Goat anti-CHATCholinergic amacrine cells
Tyrosine hydroxylase (TH)Rabbit anti-THDopaminergic amacrine cells