SDF-1β mRNA levels in the mouse brain after peripheral LPS administration
| 3 hr saline | 0.5 hr LPS | 1 hr LPS | 3 hr LPS | 6 hr LPS | 24 hr LPS | |
|---|---|---|---|---|---|---|
| SDF-1β mRNA | 381 ± 36 | 289 ± 26 | 275 ± 44 | 133 ± 82* (34%) | 138 ± 92* (36%) | 203 ± 57*(53%) |
SDF-1β mRNA levels of whole-brain sections expressed in nanoCuries per gram ± SD (mean values of four animals in the group 3 hr after saline injection and three animals per LPS-treated group). Bold values express measurements as percentage of the group 3 hr after saline injection. *p < 0.05 versus the saline-injected group. One-way ANOVA followed by Dunnett's multiple comparison test.