Infarct volumes of wild-type and metallothionein-I/-II knock-out mice (MT−/−)
| Wild-type | MT−/− | Power | p | |
|---|---|---|---|---|
| Infarct volumedirect | 31 (0) | 101 (24) | 1.0 | <0.001 |
| Infarct volumeindirect | 26 (7) | 75 (16) | 1.0 | <0.001 |
| Infarct volumerelative | 15 (5) | 43 (8) | 1.0 | <0.001 |
| Edema | 6 (7) | 26 (14) | 1.0 | <0.001 |
| Deceased animals | 0 | 4 | ||
| Included animals | 14 | 9 |
Edema and direct and indirect infarct volume are given in mm3; relative infarct size is shown in percentage of the contralateral hemisphere. Different volumes were measured to control a hypothetical (inverse) influence of brain swelling (edema) on the infarct sizes. Values are stated as mean; SD is given in brackets. Statistical analysis was performed by using the two-tailed ttest. In all groups that passed a test of normal distribution, a power analysis was performed. No inverse effect of edema on infarct sizes has been observed.