Table 1.

Laminal distribution of apoptotic cells

GroupI–IIIII–IVV–VI
Saline bolus0.5  ± 0.30.2  ± 0.20.3  ± 0.3
10 μg MS bolus8.7  ± 0.6*0.3  ± 0.11.1  ± 0.31-160
20 μg MS bolus10.7  ± 1.31-1650.5  ± 0.11.6  ± 0.41-160
Saline infusion0.4  ± 0.20.2  ± 0.20.2  ± 0.4
10 nmol·μl−1·hr−1 MS8.1  ± 1.5*0.4  ± 0.30.6  ± 0.3
20 nmol·μl−1·hr−1 MS11.9  ± 0.71-1650.6  ± 0.10.9  ± 0.41-160
  • The data represent the mean ± SE number of apoptotic cells in a given group averaged from five or six sections per rat.

  • * p < 0.01;

  • F1-160 p < 0.05, compared with the saline group,

  • F1-165 p < 0.01 compared with both saline and 10 μg or 10 nmol·μl−1·hr−1 morphine (MS) groups.