Preliminary data showing mean percent correct on the delayed alternation task after administration of guanfacine
| Dose of guanfacine (mg/kg) | 0.0 | 0.0001 | 0.001 | 0.01 | 0.1 | 1.0 |
|---|---|---|---|---|---|---|
| Wild-type mice (n = 4–7) (delays 0–20 sec) (mean ± SEM) | 71.4 ± 3.5 | 70.0 ± 3.5 | 67.1 ± 6.6 | 57.5 ± 6.0 | 74.0 ± 7.6 | 80.3 ± 2.9 |
| α2A mutant mice (n = 10) (delays 0–5 sec) (mean ± SEM) | 70.4 ± 2.1 | 62.0 ± 4.9 | 70.0 ± 2.4 | 72.4 ± 3.3 | 66.0 ± 3.2 | 70.0 ± 2.3 |