Table 1.

Comparison of Ih steady-state activation in CA3 and CA1 pyramidal neurons of different ages

CA3CA1p1-a
V1/2knV1/2knV1/2k
AgeP1−93.4  ± 0.910.3  ± 0.94−94.0  ± 0.57.9  ± 0.56NS***
P5−92.2  ± 0.89.2  ± 0.712−91.8  ± 0.68.4  ± 0.511NS**
P10−88.1  ± 0.48.9  ± 0.39−92.6  ± 0.510.3  ± 0.49******
P20−85.7  ± 0.58.5  ± 0.47−92.0  ± 0.610.4  ± 0.510******
p1-b(P1 vs P5)******NS
(P1 vs P10)********
(P1 vs P20)********
Linearity************

  • A summary of parameters derived from fits of the Boltzman relationship G/Gmax = 1/{1 + exp[(V −V1/2)/k]} to theG/Gmax data presented in Figure 7 is shown. Statistical comparisons are as indicated. Asterisks indicate statistical significance, as described in the legend to Figure 3.

  • ↵F1-a Student's t test.

  • ↵F1-b Dunnett multiple comparisons test.