General response properties of nociceptive neurons follow intrathecal injection of vehicle, SAP, or SP-SAP
| Vehicle (n = 42) | SAP (n = 20) | SP-SAP (n = 42) | ||||
|---|---|---|---|---|---|---|
| WDR | HT | WDR | HT | WDR | HT | |
| Number of neurons (%) | 27 (64%) | 15 (36%) | 13 (65%) | 7 (35%) | 39 (93%) | 3 (7%) |
| Mean ± SEM mechanical threshold (mN) | 13.4 ± 1.7 | 174.2 ± 34.1 | 16.4 ± 2.7 | 183.8 ± 45.3 | 16.1 ± 2.4 | 155.5 ± 22.0 |
| Mean ± SEM number of impulses to 178 mN | 36.6 ± 6.0 | 5.0 ± 1.3 | 38.0 ± 3.3 | 8.9 ± 2.4 | 35.9 ± 8.3 | 4.3 ± 1.7 |
| Mean ± SEM response threshold (°C) | 43.6 ± 0.7 | 44.4 ± 1.1 | 44.1 ± 0.9 | 45.0 ± 1.4 | 43.1 ± 0.5 | 46.3 ± 2.4 |