Summary of the melatonin release rhythms
| Number of animals | Period (hr ± SEM) R + LP | % Abnormal | |||||
|---|---|---|---|---|---|---|---|
| Total | R | LP | AR | AR | Total (AR + LP) | ||
| XCLΔQ-GFP | 24 | 7 | 2 | 151-165 | 26.4 ± 1.5 | 62.5 | 71.0 |
| Wild type | 23 | 20 | 1 | 2 | 24.6 ± 0.6 | 8.7 | 13.0 |
Circadian rhythmicity of melatonin release was analyzed using FFT-NLLS. Total % abnormal includes both arrhythmic and rhythmic eyes with long periods (>28 hr). R, rhythmic (period range between 20 and 28 hr); LP, long period (>28 hr); AR, arrhythmic (no significant rhythm at a 95% level of confidence).
↵F1-165 indicates significant difference between wild-type and transgenic eyes determined by Fisher's exact test (p < 0.001).