Effect of nicotine self-administration on the phenotype of the newly born cells in the dentate gyrus
| Groups | BrdU–GFAP (%) | BrdU–NeuN (%) | Total number of BrdU-labeled astrocytes | Total number of BrdU-labeled neurons |
|---|---|---|---|---|
| Control | 7.11 ± 0.67 | 63.83 ± 1.97 | 131.74 ± 18.46 | 1190.60 ± 73.15 |
| Nic 0.2 mg/kg/inf | 9.25 ± 2.65 | 58.92 ± 3.25 | 180.17 ± 63.29 | 993.29 ± 142.77 |
| Nic 0.4 mg/kg/inf | 8.84 ± 1.26 | 54.26 ± 2.06 | 96.69 ± 13.07 | 551.74 ± 29.151-165 |
| Nic 0.8 mg/kg/inf | 6.57 ± 3.34 | 53.05 ± 3.01 | 109.42 ± 37.41 | 633.95 ± 25.531-165 |
↵F1-165 p < 0.001 in comparison with the control group.