Number of Purkinje cells in wild-type and SRC-1−/− mice1-a
| Age | Genotype | n1-b | PC/section1-c |
|---|---|---|---|
| P0 | WT | 5 | 375 ± 20 |
| SRC-1−/− | 5 | 15 ± 4.61-d | |
| P5 | WT | 5 | 639 ± 16 |
| SRC-1−/− | 5 | 508 ± 201-e | |
| P10 | WT | 6 | 682 ± 24 |
| SRC-1−/− | 6 | 637 ± 32 |
↵F1-a Midsagittal sections of the cerebella were prepared from WT and SRC-1−/− mice with the ages indicated. The calbindin-positive Purkinje cells were identified by immunostaining.
↵F1-b n, Number of animals in each genotype group.
↵F1-c PC/section, Number of Purkinje cells per section was presented as mean ± SEM. The average number of Purkinje cells per section for each mouse was calculated according to the counts of Purkinje cell on three adjacent midsagittal sections. The mean value of Purkinje cells per section for each genotype was the average of all mice in the same genotype group.
↵F1-d p < 0.001 when compared with WT in the t test.
↵F1-e p < 0.005 when compared with WT in the t test.