Changes in latency to firing first action potential with drug exposure, determined at the lowest current step at which spike firing was evoked
| Condition | Baseline (msec) | After drug exposure (msec) | Change in latency (msec)* |
|---|---|---|---|
| SKF81297 + quinpirole | 160 ± 35 | 95 ± 18 | —66 ± 27 |
| DA | 162 ± 28 | 92 ± 14 | —70 ± 25 |
| Forskolin | 179 ± 22 | 66 ± 17 | —113 ± 24 |
| 4-AP (10 μm) | 166 ± 20 | 77 ± 17 | —89 ± 16 |
| 4-AP (60 μm) | 193 ± 21 | 53 ± 11 | —140 ± 15 |
| α-dtx | 174 ± 13 | 68 ± 26 | —106 ± 16 |
SKF81297 and quinpirole (10 and 10 μm) and DA (75 μm) are from perforated patch experiments.
↵* p < 0.05 for all conditions; paired t test.