Table 1.

Weight and metabolic variables in C57BL/6 and Apo E-deficient mice

Mice type Mice weight (g) Livers weight (g) Total cholesterol (mg/dl) VLDL+IDL+LDL (mg/dl) HDL (mg/dl) Triglycerides (mg/dl) Glycemia (mg/dl)
C57BL/6 wild-type mice 33 ± 1 1.2 ± 0.1 96 ± 6 37 ± 4 58 ± 2 68 ± 7 173 ± 6
Apo E-deficient mice 33 ± 2 1.3 ± 0.1 545 ± 87 ** 528 ± 84 ** 16 ± 2 ** 121 ± 11 * 201 ± 5 *
Apo E-deficient and F 35 ± 3 2.9 ± 0.2 732 ± 74 ** 728 ± 73 **# 3 ± 0.3 **## 111 ± 10 * 115 ± 5 *##
C57BL/6 wild-type mice 31 ± 1 1.2 ± 0.1 85 ± 9 32 ± 6 53 ± 3 61 ± 9 188 ± 29
Wild-type mice and F 28 ± 1 2.2 ± 0.1 78 ± 10 30 ± 7 48 ± 2 53 ± 6 183 ± 37
  • p<0.0001

  • ** p<0.001

  • * p<0.01

  • # p<0.05 versus wild-type mice

  • ## p<0.001 versus untreated Apo E-deficient mice. F, Fenofibrate.