Evoked potential measurements (mean ± SEM) averaged for baseline (pretetanus) and for 10 - 60 min post-tetanus
| fEPSP slope | Population spike amplitude | ||||
|---|---|---|---|---|---|
| Experimental condition | n | Pretetanus (mV/msec) | Post-tetanus (mV/msec) | Pretetanus (mV) | Post-tetanus (mV) |
| Unlesioned control | 4 | 0.81 ± 0.23 | 0.83 ± 0.22 | 0.56 ± 0.29 | 0.68 ± 0.36 |
| Lesioned, vehicle treated | 6 | 0.87 ± 0.07 | 1.06 ± 0.07** | 0.31 ± 0.06 | 0.51 ± 0.13* |
| Lesioned, FN-439 treated | 6 | 0.93 ± 0.13 | 0.90 ± 0.11 | 0.24 ± 0.07 | 0.26 ± 0.09 |
*p < 0.05 and **p < 0.01, comparing post-tetanus to pretetanus within each experimental condition (repeated measures ANOVA).