Table 1.

Horizontal activity after acute administration of muscimol

Muscimol dose: ng/0.25 μl per side bilaterally
01520
Lateral hypothalamus331  ± 145443  ± 102196  ± 581-a141  ± 491-a
Dorsomedial hypothalamus266  ± 81264  ± 70157  ± 19142  ± 301-a
Ventral tegmental area512  ± 44649  ± 115797  ± 236772  ± 2091-a
Nucleus of the solitary tract128  ± 54127  ± 21146  ± 91-a38  ± 13
  • Mean (±SEM) values of horizontal activity after bilateral administration of various doses of muscimol into regions that prevented intra-accumbens DAMGO-induced feeding.

  • F1-a Dose of muscimol that significantly blocked feeding in previous experiment.