Table 1.

Effects of topical lysolecithin treatment on afferent fiber numbers

NerveTreatmentSideAverage number of axons per 292 mm2 EM image
A-fibersC-fibers
SciaticLysolecithinIpsi6.8  ± 1.545.1  ± 9.0
LysolecithinContra7.9  ± 2.242.9  ± 8.9
ShamIpsi6.7  ± 3.339.3  ± 7.3
SaphenousLysolecithinIpsi10.1  ± 0.560.1  ± 2.0
LysolecithinContra11.8  ± 0.262.9  ± 1.9
ShamIpsi9.7  ± 0.357.3  ± 1.3
  • EM images were analyzed to count profiles characteristic of C-fiber axons or A-fiber axons that were either still myelinated or had been demyelinated to varying degrees. No differences were apparent in the number of A-fiber or C-fiber axons between lysolecithin-treated and control animals. Ipsi, Ipsilateral; Contra, contralateral.