p values from the statistical analysis of the effects of restraint on c-fos mRNA expression in areas of the forebrain and modulation of this expression by concomitant central infusion of oxytocin or vasopressin
| Saline | Oxytocin treatment | Vasopressin treatment | |||||
|---|---|---|---|---|---|---|---|
| Restraint | Restraint | Peptide | Interaction | Restraint | Peptide | Interaction | |
| Telencephalon | |||||||
| Piriform cortex | 0.004 | <0.001 (F(1,36) = 28.4) | NS | <0.001 (F(1,26) = 17.3) | NS | ||
| Dorsal endopiriform nucleus | 0.05 | 0.01 (F(1,37) = 7.2) | NS | 0.04 (F(1,26) = 4.8) | NS | ||
| Medial amygdala | <0.001 | <0.001 (F(1,41) = 55.3) | NS | <0.001 (F(1,28) = 56.0) | 0.032 (F(1,28) = 5.1) | 0.017 (F(1,28) = 6.5) | |
| BNST (principle nucleus) | NS | NS | NS | NS | NS | ||
| LSV | 0.01 | <0.001 (F(1,41) = 12.3) | 0.009 (F(2,41) = 5.2) | 0.07 (F(2,41) = 2.8) | 0.01 (F(1,25) = 7.7) | NS | |
| Dorsal hippocampus | |||||||
| CA1 | 0.015 | 0.03 (F(1,33) = 5.2) | 0.02 (F(2,33) = 4.5) | 0.008 (F(2,33) = 5.6) | 0.008 (F(1,24) = 8.3) | NS | |
| CA2 | 0.003 | 0.04 (F(1,33) = 4.5) | 0.05 (F(2,33) = 3.3) | 0.005 (F(2,33) = 6.2) | 0.001 (F(1,24) = 13.5) | NS | |
| CA3 | 0.003 | 0.07 (F(1,34) = 3.6) | 0.01 (F(2,34) = 5.2) | 0.002 (F(2,34) = 7.8) | 0.002 (F(1,24) = 12.2) | NS | |
| CA4 | 0.007 | 0.02 (F(1,32) = 5.8) | 0.02 (F(2,32) = 4.6) | 0.007 (F(2,32) = 5.8) | 0.01 (F(1,24) = 7.7) | NS | |
| Dentate gyrus | 0.02 | 0.05 (F(1,33) = 4.3) | 0.02 (F(2,33) = 4.5) | 0.04 (F(2,33) = 3.6) | 0.02 (F(1,22) = 6.9) | NS | |
| Ventral hippocampus | |||||||
| CA1 dorsal | 0.025 | NS | NS | 0.005 (F(1,27) = 9.5) | NS | ||
| CA1 ventral | 0.02 | NS | NS | 0.05 (F(1,24) = 4.4) | NS | ||
| CA2 | NS | NS | NS | NS | NS | ||
| CA3 | NS | NS | NS | NS | NS | ||
| CA4 | 0.007 | 0.03 (F(1,36) = 5.5) | NS | 0.02 (F(1,27) = 6.4) | NS | ||
| Dentate gyrus | 0.002 | NS | NS | 0.002 (F(1,36) = 7.5) | 0.03 (F(1,27) = 5.6) | NS | |
| Diencephalon | |||||||
| Habenula | 0.015 | 0.02 (F(1,40) = 5.8) | NS | 0.02 (F(1,27) = 6.2) | NS | ||
| PVN | 0.005 | 0.003 (F(1,41) = 9.9) | 0.003 (F(2,41) = 6.5) | 0.003 (F(2,41) = 6.5) | <0.001 (F(1,26) = 14.7) | NS | |
| Anterodorsal thalamus | 0.09 | 0.02 (F(1,42) = 6.8) | NS | NS | NS | ||
| Anteroventral thalamus | NS | NS | NS | NS | NS | ||
| Paraventricular thalamus | 0.05 | 0.03 (F(1,42) = 4.8) | NS | 0.02 (F(1,28) = 6.6) | NS | ||
| Dorsomedial hypothalamus | NS | NS | NS | NS | NS | ||
| Mesencephalon | |||||||
| Ventral tegmentum | 0.02 | <0.001 (F(1,40) = 17.1) | NS | <0.001 (F(1,26) = 25.1) | NS | ||
The first column shows the level of significance of the restraint-induced increase in c-fos mRNA expression in saline-infused controls (Student's t tests). Subsequent columns show the modulation of the c-fos response to restraint by either oxytocin or vasopressin (values shown are derived from separate two-way ANOVA). NS, p > 0.05.