Table 1.

Time course of the nystagmus evoked by ipsilateral drug injections into the PH nucleus

Drug Tm (min) T50 (min)
Carbachol 9.9 ± 0.3 18.6 ± 1.0
McN-A-343 2.6 ± 0.4 15.3 ± 4.0
Atropine 7.4 ± 0.2 22.5 ± 3.6
Pirenzepine 3.8 ± 0.4 22.8 ± 3.6
  • Tm, Time necessary to reach the maximum effect; T50, time elapsed between the injection and the moment at which 50% of the maximum effect was obtained in the response decay curve. Data are shown as means ± SEM. Data were collected from four or more effective injections of each drug.