Drug | Tm (min) | T50 (min) |
---|---|---|
Carbachol | 9.9 ± 0.3 | 18.6 ± 1.0 |
McN-A-343 | 2.6 ± 0.4 | 15.3 ± 4.0 |
Atropine | 7.4 ± 0.2 | 22.5 ± 3.6 |
Pirenzepine | 3.8 ± 0.4 | 22.8 ± 3.6 |
Tm, Time necessary to reach the maximum effect; T50, time elapsed between the injection and the moment at which 50% of the maximum effect was obtained in the response decay curve. Data are shown as means ± SEM. Data were collected from four or more effective injections of each drug.