Table 2.
Model mechanisms
| Na+ channel | |
| iNa = ḡNam3h (V-ENa), ENa = 74 mV |  , τh = 1/(αh + βh) |
 | h∞ = 1/(1+e(V+60)/4) |
| αm = -0.08(V+76)/(e-(V+76)/3.5 - 1) | αh = 0.053(V + 62.4)/[1 - e- (V + 62.4)/8] |
| βm = 0.65(V + 34)/[e(V + 34)/4 - 1] | βh = - 0.004(V + 90)/[1 - e(V + 90)/5.6] |
| Delayed rectifier K+ channel | |
| iK = ḡKn4(V - EK), EK = - 105 mV | αn = -0.022 (V + 20)/[e-(V + 20)/12 - 1] |
 | βn = 0.0048 (V + 8)/[e(V + 8)/19 - 1] |
| High-threshold Ca2+ channel | βm = 0.1 e-V/20 |
 | |
 | αh = 0.000168 e-V/36.76 |
 | βh = 1/[1 + e(-V + 56.94)/18.11] |
| αm = 0.25 (-V + 35)/[e(-V + 35)/10 - 1] | [Ca2+]0 = 2 mm, [Ca2+]i (rest) = 50 nm |
| Ca-Orange (B) and endogenous buffer (S) |  |
 |  mm-1 msec-1,  μm |
 | BT = 150 μm,  mm-1 msec-1 |
| [CaB] + [B] = BT, [CaS] + [S] = ST |  μm, ST = 1.4 mm, F = 96,485 C mol-1 |
 | d(x) = d0e-x/λT,  |
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Model equations describing intrinsic membrane conductances, calcium buffers, and fluorescence. V, Transmembrane voltage; [Ca2+]i, free calcium ion concentration; [B] and [CaB], concentrations of free and calcium-bound forms of Calcium Orange; [S] and [CaS], concentrations of free and calcium-bound forms of endogenous buffer.