Corticostriatal cytoarchitecture in DD and control mice
| Control adult | DD adult | Control pup (P15) | DD pup (P15) | |
|---|---|---|---|---|
| Number of mice | 9 | 4 | 5 | 5 |
| Number of synapses analyzed | 272 | 118 | 194 | 163 |
| Glutamate density (gold particles/μm2 within a terminal) | 92.6 ± 8.5 | 88.6 ± 5.9 | 75.6 ± 5.4 | 89.2 ± 11.0 |
| Properties of asymmetrical synapses Percentage of synapses with contacts on dendritic shafts | 4.7 ± 1.4 | 11.4 ± 4.0 | 5.8 ± 1.4 | 8.0 ± 1.6 |
| Percentage of synapses with perforations | 9.8 ± 2.0 | 14.1 ± 1.4 | 7.8 ± 2.0 | 5.6 ± 3.4 |
| Percentage of synapses with multiple contacts/terminal | 3.3 ± 1.7 | 5.1 ± 2.0 | 4.1 ± 2.1 | 2.3 ± 1.0 |
Data are expressed as mean ± SEM.