Table 1.

Timing (in seconds) of phasic LC and behavioral responses to task cues

Phasic LC response
Stimulus-locked Response-locked Behavioral
PETH Onset Peak Onset Peak RT (sec ± SD)
Individual session correct 0.22 ± 0.01 0.35 ± 0.02 −0.21 ± 0.02 −0.10 ± 0.01
Population correct 0.11 0.28 −0.24 −0.10 0.426 ± 0.127
Population incorrect 0.14 0.32 −0.24 −0.09 0.513 ± 0.207
Population fast correct 0.10 0.25 −0.23 −0.11 0.343 ± 0.034
Population slow correct 0.14 0.30 −0.24 −0.10 0.504 ± 0.140
Population fast incorrect 0.15 0.26 −0.23 −0.10 0.376 ± 0.101
Population slow incorrect 0.19 1.01 −0.23 −0.10 0.793 ± 0.267
Population nonrewarded 0.10 0.21 −0.22 −0.09 0.379 ± 0.117
Population noncue 0.16 0.26 −0.24 −0.09 0.549 ± 0.209

  • For stimulus-locked PETHs, values represent LC response latencies after the visual cue. Latencies for response-locked PETHs reflect the time of LC response before the lever release. “Individual session correct” values give mean ± SEM onset and peak latencies for individual LC PETHs (not normalized). This analysis was not feasible for incorrect and noncue data because of the small numbers of these trials in daily sessions. Note the similarities in the response-locked onset and peak values for the individual and population correct PETHs. Onset and peak latencies for the PETHs were rounded to the nearest hundredth of a second because the individual PETHs used to compile each population PETH had a bin width of 0.01 sec.