Microelectrode recordings from mouse diaphragm
| MEPP | MEPC | Quantal content of EPP | ||||||
|---|---|---|---|---|---|---|---|---|
| Mouse | n | Amplitude (mV) | Amplitude (msec) | n | Amplitude (nA) | Amplitude (msec) | n | |
| Control (C57BL/6) | 49 | 0.89 ± 0.036 | 1.45 ± 0.041 | 31 | 2.27 ± 0.090 | 0.55 ± 0.017 | 29 | 42.8 ± 2.6 |
| α-Syntrophin null | 32 | 0.69 ± 0.020 (p < 0.001) | 1.31 ± 0.057 (p < 0.05) | 45 | 2.09 ± 0.087 (p, NS) | 0.39 ± 0.023 (p < 0.001) | 28 | 49.4 ± 3.4 (p, NS) |
| α/β2-Syntrophin null | 47 | 0.73 ± 0.025 (p < 0.001) | 1.53 ± 0.056 (p, NS) | 42 | 1.71 ± 0.059 (p < 0.001) | 0.39 ± 0.022 (p < 0.001) | 17 | 39.1 ± 3.9 (p, NS) |
Values indicate mean ± SE; n indicates the number of endplates examined. NS, Not significant.