Effects of 1-2 nm AP-Sema3F on rise time and decay time constants of mEPSCs recorded from adult mouse DG granule cells and CA1 pyramidal neurons
| Mouse, mEPSC properties | AP (1-2 nm) | AP-Sema3F (1-2 nm) | p values, two-tailed t test; α = 0.05 |
|---|---|---|---|
| DG | |||
| mEPSC rise time (10-90% of peak, msec) | 1.78 ± 0.03 | 1.68 ± 0.02 | p < 0.01* |
| mEPSC decay time constant (msec) | 3.82 ± 0.06 | 3.66 ± 0.03 | p < 0.05* |
| CA1 | |||
| mEPSC rise time (10-90% of peak, msec) | 1.86 ± 0.02 | 1.97 ± 0.02 | p < 0.01* |
| mEPSC decay time constant (msec) | 4.28 ± 0.08 | 4.63 ± 0.30 | p < 0.01* |
↵* α = 0.05, statistical significance using two-tailed t test.