Table 1.

Effect of growth factor overexpression on SC survival, recruitment, and differentiation in vivo

Series Anti-human nuclei+ cells GFP+ cells PO+ structures GFP+/PO+ structures GFP-/PO+ structures
Lesion 0 0 6 ± 2.7 0 6 ± 2.7
GFP 254 ± 32 188 ± 47 48 ± 11 26 ± 7 22 ± 5.8
BDNF 328 ± 49 264 ± 72 457 ± 82 31 ± 6 426 ± 71
NT-3 421 ± 27 368 ± 82 492 ± 91 127 ± 45 365 ± 82
  • Data represent the number of GFP+ cells and PO+ and GFP+/PO+ structures ± SEM per lesion in the four experimental series (n = 20 per series). Statistical differences were obtained between all groups for p < 0.001.