Latencies of the prS-evoked responses in superficial layers of the MEA as recorded in vivo in eight control and six chronic epileptic rats at 2–4 months after induction of SE with KA
| Latency onset (ms) | Latency peak (ms) | Peak amplitude (mV/mm2) | Duration (ms) | Area under curve (ms × mV/mm2) | |
|---|---|---|---|---|---|
| Control | |||||
| n1 (4:8) | 1.08 ± 0.18 | 1.75 ± 0.29 | |||
| Negative deflection MEA-III (asterisk in fig. 3D; 8:8) | 3.80 ± 0.52 | 6.82 ± 0.51 | |||
| n2 (observed 8:8; measured 6:8) | 8.74 ± 0.70 | 234 ± 42 | |||
| n3 (observed 8:8; measured 5:8) | 9.04 ± 0.60 | 24.36 ± 2.27 | 1479 ± 279 | ||
| Epileptic | |||||
| n1 (3:6) | 0.97 ± 0.04 | 1.53 ± 0.04 | |||
| Negative deflection MEA-III (asterisk in Fig. 4B; 6:6) | 3.64 ± 0.54 | 7.79 ± 0.56 | |||
| n2 (6:6) | 8.71 ± 0.59 | 84 ± 16* | |||
| n3 (6:6) | 7.5 ± 0.61 | 25.99 ± 6.07 | 1517 ± 507 |
Latencies of events were calculated from the three-point CSD analysis of the data. Responses were measured at the stimulus intensity that yielded the maximal response. Values are means ± SEM.
↵* p < 0.01 (compared with controls; Mann—Whitney U test).