Table 1.

Number of plaques per ROI by age and image type

In vivoEx vivo Thio-S
Age (months) Mean SD CV Mean SD CV Mean SD CV
3 0.83 0.40 0.48 4.00 0.30 0.08
6 2.38 0.70 0.29 7.80 0.50 0.06
9 0.61 0.60 0.98 4.68 0.80 0.17 8.83 0.60 0.07
12 1.46 0.50 0.34 7.28 0.80 0.11 12.04 0.60 0.05
24 7.06 1.00 0.14 9.14 0.60 0.07 25.00 0.90 0.04

  • Values for 3- and 6-month-old mice on in vivo MRI are not shown. CV, Coefficient of variation.