Table 2.

PIB binding to homogenates from 15-month-old PS1/APP and PS1 mice and human AD and control brain in the presence of 1 nm [3H]PIB

PIB bound (pmol/g wet weight) Fold difference
PS1/APP (n = 4) 166 ± 61 3.5
PS1 (n = 4) 47.5 ± 51
Human AD (n = 4) 415 ± 51 16.3
Human control (n = 3) 25.4 ± 46