Table 3.

Summary of the estimated properties of AMPA receptors in hot spots with single and multiple synapses

Single synapse Multiple synapses
Distance from the neighboring synapse r > 2.3 μm r < 2.3 μm
10-90% rise time (ms) 2.7 ± 0.7 3.6 ± 0.4
62% decay time (ms) 15.3 ± 3.2 17.8 ± 2.0
Single-channel conductance (pS) 8.0 ± 1.1 11.6 ± 1.1
Number of AMPA receptors 154 ± 56 90 ± 6
Peak open probability 0.57 ± 0.08 0.60 ± 0.05
Density of AMPA receptors (/μm2) 1630 ± 190
Number of samples 3 5
  • Values were not corrected for RC filtering and are expressed as mean ± SEM. The density of AMPA receptors was estimated only from single synapses.