NAA concentrations measured by 1H-MRSI and RP-HPLC from the midbrains of mice 2 d after MPTP treatment
| Midbrain NAA levelsA | ||
|---|---|---|
| Treatment | MRSI (mm) | HPLC (μmol/g tissue) |
| PBS | 9.1 ± 0.4 | 16.5 ± 1.5 |
| MPTP | 7.1 ± 0.2* | 11.0 ± 1.4 |
| MPTP/Cop-1 | 9.3 ± 1.0 | 17.5 ± 2.3 |
| MPTP/OVA | 7.6 ± 0.7* | 13.7 ± 1.4 |
a Mean ± SEM for five to nine mice per group.
↵* p ≤ 0.05 compared with PBS-treated mice.