MAP and HR before (baseline) and during CRD in naive uninjured rats and those with T4 spinal cord transactions with subsequent intraspinal injections of adenovirus encoding GFP (control), NGF, or Sema3a at specified spinal levels
| Treatment/spinal level | MAP baseline (mmHg ± SD) | HR baseline (bpm ± SD) | MAP CRD (mmHg ± SD) | HR CRD (bpm ± SD) |
|---|---|---|---|---|
| Naive (n = 3) | 111 ± 10 | 450 ± 80 | 35.4 ± 4 | +76.2 ± 22 |
| NGF Adts/T5/6 (n = 5) | 106 ± 7 | 540 ± 50 | 22.0 ± 4 | −25.8 ± 12 |
| GFP Adts/ T13/L1(n = 5) | 106 ± 5 | 477 ± 92 | 22.5 ± 7 | −33.6 ± 24 |
| NGF Adts/ T13/L1 (n = 9) | 104 ± 8 | 475 ± 88 | 32.7 ± 5 | −43.8 ± 24 |
| GFP Adts/ L6/S1 (n = 9) | 105 ± 8 | 511 ± 86 | 21.1 ± 5 | −29.6 ± 20 |
| NGF Adts/ L6/S1(n = 8) | 102 ± 8 | 472 ± 94 | 30.5 ± 5 | −40.8 ± 27 |
| Sema3a Adts/ L6/S1 (n = 14) | 101 ± 10 | 499 ± 89 | 14.1 ± 5 | −30.6 ± 18 |