Frontal cortex | Hippocampus | |||
---|---|---|---|---|
Gene | r | Fold | r | Fold |
Adcy9 | 0.60** | (3.4) | 0.85** | (4.6) |
Akt1 | 0.77** | (2.7) | 0.41* | (2.1) |
Apoe | 0.81** | (6.6) | 0.83** | (4.9) |
App | -0.17 | (1.8) | 0.29 | (1.5) |
Bbs2 | -0.19 | (1.1) | 0.03 | (1.1) |
Camk2b | 0.18 | (1.4) | 0.38* | (1.7) |
Comt | -0.08 | (1.4) | -0.09 | (1.6) |
Drd1a | -0.38 | (1.3) | 0.08 | (1.1) |
Freq | -0.26 | (1.1) | 0.37* | (1.2) |
Gria3 | 0.61** | (2.7) | 0.46** | (1.5) |
Grin2a | 0.73** | (1.4) | 0.01 | (1.5) |
Gsk3b | 0.33 | (1.3) | 0.46* | (1.2) |
Htr2a | 0.13 | (1.1) | -0.10 | (1.1) |
Htr2c | 0.51** | (1.2) | -0.11 | (1.2) |
Impa2 | -0.17 | (1.3) | -0.03 | (1.1) |
Maoa | 0.27 | (1.7) | -0.16 | (1.6) |
Maob | 0.74** | (6.7) | 0.47** | (4.2) |
Nedd41 | 0.02 | (1.3) | -0.10 | (1.6) |
Npy | 0.07 | (2.1) | -0.17 | (1.6) |
Nsf | 0.04 | (4.3) | 0.73** | (4.5) |
Prnp | 0.59** | (2.7) | 0.64** | (1.9) |
Psen1 | 0.27 | (1.2) | 0.53** | (1.2) |
Reln | 0.66** | (1.9) | 0.82** | (3.5) |
Rgs4 | 0.78** | (8.0) | 0.25 | (2.1) |
Rtn4 | 0.11 | (1.5) | 0.16 | (1.2) |
Slc1a2 | 0.71** | (1.9) | 0.75** | (2.0) |
Sybl1 | 0.38* | (1.6) | 0.65** | (2.0) |
Syn2 | 0.66** | (8.0) | 0.63** | (6.0) |
Synj1 | 0.42* | (1.7) | 0.62** | (1.8) |
Tbp | 0.10 | (1.3) | 0.29 | (1.2) |
Tcf4 | 0.01 | (1.9) | 0.40* | (1.9) |
Th | -0.08 | (1.1) | 0.09 | (1.1) |
Xbp1 | -0.04 | (1.4) | -0.06 | (1.5) |
Correlation coefficients between data generated by RT-PCR and by microarray are presented separately for each of the 33 genes analyzed by RT-PCR. Maximum fold changes over developmental time, as determined by microarray analyses, are shown in parentheses. Significant correlations: *p < 0.05 and **p < 0.01. Adcy9, Adenylate cyclase 9; Akt1, thymoma viral proto-oncogene 1; Apoe, apolipoprotein E; App, amyloid β precursor protein; Bbs2, Bardet—Biedl syndrome 2; Camk2b, calcium/calmodulin-dependent protein kinase II β; Comt, catechol-O-methyl-transferase; Drd1a, dopamine receptor 1A; Freq, frequenin homolog; Gria3, glutamate receptor, ionotropic, AMPA3; Grin2a, glutamate receptor, ionotropic, NMDA 2A; Gsk3b, glycogen synthase kinase 3β; Htr2a, 5-hydroxytryptamine receptor 2A; Htr2c, 5-hydroxytryptamine receptor 2C; Impa2, inositol(myo)-1(or 4)-monophosphatase 2; Maoa, monoamine oxidase A; Maob, monoamine oxidase B; Nedd41, neural precursor cell expressed, developmentally downregulated 4-like; Npy, neuropeptide Y; Nsf, N-ethylmaleimide-sensitive factor protein; Prnp, prion protein; Psen1, presenilin 1; Reln1, reelin; Rgs4, regulator of G-protein signalling 4; Rtn4, reticulon 4; Slc1a2, solute carrier family 1 (glial high-affinity glutamate transporter), member 2; Sybl1, synaptobrevin-like 1; Syn2, synapsin II; Synj1, synaptojanin 1; Tbp, TATA-box-binding protein; Tcf4, transcription factor 4; Th, tyrosine hydroxylase; Xbp1, X-box-binding protein 1.