Table 2.

Regions of an entire human brain functional network ranked in order of increasing path length

Abbreviation Region Class LikiCiDi ΔLnet
PCUN Precuneus Association 1.95 22.5 0.31 57.6 2.59
MTG Middle temporal gyrus Association 2.03 16.5 0.46 76.6 2.44
MFG Middle frontal gyrus Association 2.10 18.0 0.35 72.6 3.55
LING Lingual gyrus Association 2.11 21 0.54 55.8 2.07
MOG Middle occipital gyrus Association 2.14 20.5 0.55 57.0 2.33
SPG Superior parietal gyrus Association 2.14 15.5 0.43 61.7 2.23
PoCG Postcentral gyrus Primary 2.15 20 0.47 62.0 1.34
ITG Inferior temporal gyrus Association 2.18 14 0.52 95.9 1.58
PreCG Precentral gyrus Primary 2.18 20 0.44 62.4 2.49
DCG Dorsal cingulate gyrus Paralimbic 2.21 9.5 0.46 42.2 2.08
SFGdor Superior frontal gyrus (dorsal) Association 2.23 13 0.48 72.2 1.32
CAL Calcarine cortex Primary 2.23 14.5 0.73 37 0.93
STG Superior temporal gyrus Association 2.24 17 0.43 81.9 2.57
FFG Fusiform gyrus Association 2.30 16.5 0.63 63.7 3.77
SMA Supplementary motor area Association 2.39 11 0.62 49.4 1.13
CUN Cuneus Association 2.41 11 0.86 34.3 0.49
IPL Inferior parietal lobule Association 2.42 9.5 0.56 72.4 0.54
ORBsup Orbitofrontal cortex (superior) Paralimbic 2.42 9.5 0.37 67.2 3.82
IFGtriang Inferior frontal gyrus (triangular) Association 2.44 9.5 0.49 71.6 0.61
SOG Superior occipital gyrus Association 2.49 14 0.74 45.0 0.28
THA Thalamus Subcortical 2.51 8 0.51 42.8 0.83
ORBinf Orbitofrontal cortex (inferior) Paralimbic 2.61 6 0.51 57.1 1.14
ORBmid Orbitofrontal cortex (middle) Paralimbic 2.66 6 0.57 59.5 -0.15
SMG Supramarginal gyrus Association 2.70 5.5 0.70 77 -0.27
PCG Posterior cingulate gyrus Paralimbic 2.73 4.5 0.68 30.4 -0.35
IOG Inferior occipital gyrus Association 2.75 6.5 0.92 58.7 -0.40
PCL Paracentral lobule Association 2.77 6 0.93 26.6 -0.43
ROL Rolandic operculum Association 2.77 7.5 0.74 62.1 -0.45
IFGoperc Inferior frontal gyrus (opercular) Association 2.78 5.5 0.62 65.0 -0.46
SFGmed Superior frontal gyrus (medial) Association 2.8 7 0.50 49.6 0.49
INS Insula Paralimbic 2.94 5.5 0.63 68.6 -0.64
ANG Angular gyrus Association 3.03 5 0.0.20 79.1 -0.89
HES Heschl's gyrus Primary 3.07 3.5 0.92 60.4 -1.21
TPOsup Temporal pole (superior) Paralimbic 3.14 5 0.42 70.7 -0.38
TPOmid Temporal pole (middle) Paralimbic 3.2 3 0.08 80.3 -0.46
REC Rectus gyrus Paralimbic 3.2 3 0.5 36 -1.53
HIP Hippocampus Limbic 3.3 3.5 0.15 34.5 -0.25
CAU Caudate Subcortical 3.35 3 1 33.6 -1.94
PHG Parahippocampal gyrus Paralimbic 3.38 2.5 0 28 -1.08
ORBsupmed Orbitofrontal cortex (superior-medial) Paralimbic 3.46 2.5 0 26.2 -2.09
  • Major “hubs” of the network are listed first. Li, Ci, and ki are the characteristic path length, clustering coefficient, and degree, respectively, of the ith region. Di is the mean Euclidean distance of connections to that region. ΔLnet is the percentage of change in global mean path length when the network is attacked by eliminating the ith region and its connections. The regions are classified as the primary, association, paralimbic, or limbic cortex as described by Mesulam (2000). Network hubs, defined as those regions with characteristic path length less than global network mean path length (2.49), are listed in bold; clustering coefficients are italicized for those hubs in which they are less than the global mean clustering coefficient (0.525).