Pharmacological treatment | Dose (mg/kg) | Forward activity during run A | Forward activity during run B | ||
---|---|---|---|---|---|
Group | Group | ||||
FH | FR | FH | FR | ||
SCH23390 | 0 | 37.8 ± 12.13 | 51.67 ± 13.45 | 76.50 ± 18.85 | 124.11 ± 35.83 |
0.015 | 42.50 ± 7.85 | 58.89 ± 17.28 | 58.10 ± 20.26 | 125.89 ± 45.35 | |
0.03 | 65.33 ± 19.84 | 51.10 ± 12.20 | 10.00 ± 3.85 | 88.44 ± 40.69 | |
Sulpiride | 0 | 93.43 ± 20.35 | 168.22 ± 30.63 | 62.00 ± 12.83 | 199.44 ± 37.22 |
25 | 92.14 ± 28.65 | 148.22 ± 25.55 | 60.14 ± 15.59 | 210.67 ± 47.23 | |
75 | 40.86 ± 12.94 | 110.22 ± 25.70 | 40.29 ± 15.27 | 138.22 ± 24.98 | |
125 | 36.29 ± 7.33 | 68.89 ± 11.42 | 32.43 ± 12.42 | 125.33 ± 24.95 | |
Naltrexone | 0 | 67.50 ± 22.97 | 102.12 ± 23.40 | 30.30 ± 12.44 | 145.00 ± 52.11 |
10 | 44.80 ± 9.13 | 59.25 ± 13.74 | 36.20 ± 9.01 | 107.12 ± 39.41 | |
20 | 21.80 ± 9.19 | 40.50 ± 14.04 | 32.30 ± 12.58 | 59.25 ± 15.94 | |
GYKI 52466 | 0 | 33.60 ± 6.80 | 86.78 ± 31.94 | 45.70 ± 18.33 | 167.55 ± 68.06 |
5 | 53.90 ± 6.34 | 79.56 ± 29.61 | 28.10 ± 10.89 | 134.89 ± 47.13 | |
10 | 41.30 ± 6.34 | 37.44 ± 8.88 | 7.00 ± 3.26 | 7.22 ± 2.36 |