The number and baseline firing rates of neurons recorded during instrumental responding task (experiment 2)
| Treatment | Session | mPFC | OFC | ||
|---|---|---|---|---|---|
| n | Baseline (Hz) | n | Baseline (Hz) | ||
| Vehicle | Day 0 | 117 | 5.88 ± 0.33 | 96 | 6.30 ± 0.33 |
| Amphetamine, 2 mg/kg | Day 1 | 104 | 6.21 ± 0.34 | 89 | 5.69 ± 0.32 |
| Amphetamine, 2 mg/kg | Day 3 | 104 | 6.94 ± 0.33 | 90 | 6.21 ± 0.34 |
| Amphetamine, 2 mg/kg | Day 5 | 112 | 6.51 ± 0.31 | 79 | 6.08 ± 0.36 |
| Amphetamine, 2 mg/kg | Challenge | 86 | 6.62 ± 0.37 | 65 | 5.45 ± 0.51 |
Although baseline firing rates during 10 min of instrumental responding were higher than spontaneous baseline rates recorded in experiment 1, there were no significant between-session difference in mPFC or OFC (one-way ANOVA, p > 0.05).