Probe set ID | Fold change | Peak level | Gene name | Gene symbol |
---|---|---|---|---|
M93669_at | −49.52 | 1827 | Secretogranin II | SCG2 |
J03627_at | −37.01 | 1855 | S100 calcium binding protein A10 | S100A10 |
rc_AA899590_at | −27.47 | 4001 | ESTs, no homologies found | |
rc_AA899854_at | −25.81 | 3481 | Topoisomerase (DNA) 2α | TOP2A |
rc_AA997800_at | −22.01 | 2285 | Antigen Ki-67 (predicted) | Ki-67 |
rc_AI228113_s_at | −19.03 | 591 | Neuronal pentraxin receptor | NPTXR |
rc_AI176963_at | −18.13 | 840 | Cbp/p300-interacting transactivator 2 | CITED2 |
J03624_at | −18.00 | 2821 | Galanin | GALN |
rc_AA963443_at | −18.00 | 996 | Cyclin D2 | CCND2 |
J02585_at | −17.27 | 5693 | Stearoyl-coenzyme A desaturase 1 | SCD1 |
rc_AA956638_at | −16.45 | 525 | Ubiquitin-like, PHD + RING finger domains 1 | UHRF1 |
rc_AA944180_at | −15.89 | 1429 | CDC28 protein kinase regulatory subunit 2 | CKS2 |
rc_AA818744_at | −15.56 | 516 | Complement comp. 1, q subcomp., receptor 1 | CD93 |
rc_AI101009_at | −14.22 | 1223 | Zinc finger, CCHC domain containing 12 | ZCCHC12 |
rc_AI010123_at | −14.12 | 1384 | Transforming, acidic coiled-coil cont. protein 2 | TACC2 |
X59864mRNA_g_at | −13.83 | 3102 | H19 fetal liver mRNA | H19 |
rc_AI231702_at | −13.74 | 341 | Centrosomal protein 152 kDa | CEP152 |
rc_AA819103_at | −13.45 | 685 | Mesoderm specific transcript homolog | MEST |
rc_AA997385_at | −13.36 | 887 | Ubiquitin specific protease 43 | USP43 |
rc_AI179576_s_at | −13.27 | 3573 | Hemoglobin, β | HBB |
X60767mRNA_s_at | −13.09 | 1163 | Cell division cycle control protein 2 | CDC2 |
rc_AI071227_at | −13.00 | 418 | DNA repair protein RAD51 homolog 1 | RAD51 |
rc_AI639088_s_at | −12.73 | 792 | ESTs, no homologies found | |
rc_AA859341_at | −12.38 | 475 | SH3 and PX domains 2A | SH3PXD2A |
U17565_g_at | −12.04 | 3466 | Mini chromosome maintenance deficient 6 | MCM6 |
rc_AI058975_at | −11.96 | 1063 | SRY-box containing gene 11 | SOX11 |
rc_AI146172_at | −11.88 | 1565 | Neuron specific gene family member 2 | NSG2 |
rc_AA900746_at | −11.88 | 485 | ESTs, no homologies found | |
M74223_at | −11.79 | 5120 | VGF nerve growth factor inducible | VGF |
rc_AI103150_at | −11.71 | 934 | Ubiquitin-conjugating enzyme E2C | UBE2C |
rc_AI010612_at | −11.47 | 254 | Tenascin C | TNC |
rc_AA956688_at | −11.39 | 2048 | Cell division cycle associated 3 | CDCA3 |
rc_AI231497_at | −11.31 | 1171 | Karyopherinα2 | KPNA2 |
rc_AA893717_at | −11.24 | 2174 | Rac GTPase-activating protein 1 | RACGAP1 |
rc_AI012221_at | −11.16 | 1413 | Chloride intracellular channel 1 | CLIC1 |
rc_AI169327_g_at | −11.08 | 957 | Tissue inhibitor of metalloproteinase 1 | TIMP1 |
rc_AI045594_at | −10.93 | 1752 | Spindle pole body component 25 | SPBC25 |
rc_AI103106_at | −10.78 | 1783 | Lamin B1 | LMNB1 |
rc_AI072698_at | −10.70 | 869 | TRAF4 associated factor 1 | TRAF4AF1 |
rc_AA851392_at | −10.63 | 537 | Kinesin family member 22 | KIF22 |
rc_AA818016_at | −10.56 | 2069 | Cell division cycle 23 | CDC23 |
rc_AI237713_at | −10.56 | 1007 | ESTs, no homologies found | |
rc_AI103682_at | −10.56 | 307 | Polymerase (DNA directed),α1 | POLA |
rc_AI232326_at | −10.48 | 989 | ESTs, no homologies found | |
rc_AI145123_at | −10.48 | 989 | Similar to ataxin 2-binding protein 1 isoform 2 | |
rc_AA925012_at | −10.48 | 1711 | Geminin | GMNN |
rc_AI104821_at | −10.34 | 460 | Leucine rich repeat interacting protein 1 | LRRFIP1 |
AF019974_at | −10.27 | 381 | Chromogranin B | CHGB |
rc_AA943886_at | −10.20 | 830 | Polo-like kinase 2 | PLK2 |
rc_AI230215_at | −10.06 | 1336 | Cell division cycle associated 8 | CDCA8 |
The 50 unique genes most strongly repressed during OL differentiation are listed. Note that genes with a likely 2A expression pattern are not included. Genes listed in bold are present in both Tables 3 and 4. In cases in which more than one Affymetrix probe set (Probe set ID) corresponding to the same gene was highly regulated, only the most strongly regulated is listed. Fold change, Highest expression level/lowest expression level in time course; negative numbers are downregulated relative to OPCs. Peak level, Highest raw level of expression seen at any time point in the gene chip experiment.