Table 1.

Taste recognition thresholds for the four basic taste modalities

TasteBefore placeboAfter placebo% ChangeBefore SSRIAfter SSRI% ChangeBefore NARIAfter NARI% Change
Bitter54 μm63 μm16% Increase30 μm14 μm53%31 μm19 μm*39%
(36–79 μm)(41–94 μm)(24–38 μm)(12–19 μm)Decrease(24 - 39 μm)(15–26 μm)Decrease*
Sweet44 mm41 mm7% Decrease23.4 mm17 mm***27%26 mm22 mm15%
(36–53 mm)(34–49 mm)(21–28 mm)(14–19 mm)Decrease***(22–30 mm)(18–25 mm)Decrease
Salt29 mm26 mm10% Decrease19 mm19 mm21 mm23 mm9%
(21–37 mm)(19–33 mm)(16–21 mm)(18–24 mm)(20–26 mm)Increase
Sour9 mm9 mm10 mm8 mm20%9 mm7 mm*22%
(7–13 mm)(8–13 mm)(8–11 mm)(6–9 mm)Decrease(8–10 mm)(6–8 mm)Decrease*
  • Data shown are means (95% confidence intervals). Statistical comparisons of the threshold values were compared to baseline values using an F test:

  • *p < 0.05,

  • **p < 0.01,

  • ***p < 0.001, and

  • p < 0.0001 compared with baseline responses;

  • p < 0.05 compared with before placebo thresholds.