Description of the well characterized transgenic C. elegans used in the study
| Strains | Transgene | Expression | Phenotype |
|---|---|---|---|
| N2 | Wild type | Wt movement | |
| CL4176 | myo-3/Aβ1–42 | Inducible muscle Aβ1–42 | Rapid paralysis |
| CL1175 | myo-3 | Control for CL4176 | Normal |
| CL2006 | unc-54/Aβ1–42 | Constitutive muscle Aβ1–42 | Progressive paralysis |
| CL2355 | snb-1/Aβ1–42 | Inducible neuronal Aβ1–42 | Reduced chemotaxis |
| Hypersensitive to 5-HT | |||
| CL2122 | mtl-2/GFP | Control for CL2355 | Wt movement |
| CL2179 | myo-3/GFP | GFP control for CL4176 | Wt movement |
Wt, Wild type.