Table 3.

Dimensions of hydrated proton, small chemical molecules, and proteins

MoleculeMw (g/mol)XYZ dimensions (nm)aDatabase accession number
Hydrated proton (H3O+)190.1 (O-H) × 0.2 (H-H) × 0.2 (H-H)13968-08-6 (CAS)
HEPES2380.5 × 1.0 × 0.37365-45-9 (CAS)
FM 4-64b6080.9 × 3.0 × 0.3
Human ANP∼3 × 1032.1 × 2.1 × 1.11ANP (PDB) (Cunningham et al., 1994)
GFP mutant∼27 × 1033.8 × 5.1 × 3.62EMO (PDB) (Palm et al., 1997)
Human prolactin∼23 × 1035.2 × 6.4 × 3.31RW5 (PDB) (Teilum et al., 2005)
  • O-H, Oxygen atom to hydrogen atom; H-H, between two hydrogen atoms; CAS, Chemical Abstracts Service numbers for small chemical molecules; PDB, Protein Data Bank numbers for proteins; ANP, atrial natriuretic peptide; GFP, green fluorescent protein.

  • aXYZ dimensions of molecules were measured with a Pymol Molecular Graphics System.

  • bThree-dimensional model of FM 4-64 was obtained with MDL ISIS/Draw (version 2.5) and a Pymol Molecular Graphics System.