Summary of pharmacological effects in vitro
| Treatments | Total n | Phospho-ERK1/2 levels in parvicellular PVH | |||
|---|---|---|---|---|---|
| − | + | ++ | +++ | ||
| Agonist only | |||||
| NE (100 μm) | 4 | 0 | 0 | 1 | 3 |
| NE (200 μm) | 4 | 0 | 0 | 0 | 4 |
| Control/antagonist | |||||
| aCSF | 3 | 3 | 0 | 0 | 0 |
| Prazosin (10 μm) + NE (100 μm) | 5 | 2 | 1 | 1 | 1 |
| U0126 (10 μm) + NE (100 μm) | 4 | 3 | 0 | 1 | 0 |
The numbers in this table denote the number of slices demonstrating parvicellular PVH phospho-ERK1/2 absence/presence, depending on the signal strength. −, Absent; +, low; ++, moderate; +++, strong.