Table 1.

Overview of the number of animals included in different experiments

Experiment/groupNoninjuredMethodology
ISHqRT-PCR (24 h)Arrays (24 h)ImmunohistochemistryHistology (7 d)Behavior (49 d)
1.5 h6 h24 h3 d4 d
Experiment 1
    C57BL/6J266536812
    TLR2-ko25553812
    MyD88-ko255336812
    C3H/HeOUJ14553812
    TLR4d14553812
Experiment 2
    Lesion only610
    PBS2a8a10b610
    Zymosan2a8a10b610
    LPS2a8a10b710
Experiment 3
    Control610
    DEX2511
    MP2611
  • aUninjured rats given microinjections of PBS, zymosan, or LPS into their left sciatic nerve.

  • bTwo of these 10 rats were uninjured.